PRO-E0258
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More information| Catalogue No. | PRO-E0258 |
|---|---|
| EC | 4.2.1.84 |
| Synonyms | Nitrilase; 3-cyanopyridine hydratase; NHase; LNHase; H-NHase; acrylonitrile hydratase; aliphatic nitrile hydratase; nitrile hydro-lyase; aliphatic-amide hydro-lyase (nitrile-forming) |
| Nomenclature | Co-type |
| Specific Activity | 21.97 U/mg |
| Accession No. | Q6N613 (?-subunit) | Q6N612 (?-subunit) |
| Molecular Weight | 25878.9 Da (?-subunit) | 24204.3 Da (?-subunit) |
| Biological Function | Acts on nitriles | converting them into the corresponding acid amides (note: does not act on these amides) |
| Comments | Co-type nitrile hydratase. Active on aryl and alkyl nitriles | and a wider range of heteroaryl nitriles than PRO-E0256. Active in water/DMSO mixtures | and water/MeOH. Monohydration of bis-nitriles. Selective nitrile hydration in the presence of ester functionality. Regio- and stereoselective. This enzyme is heterodimeric | comprising one ?- and one ?-subunit |
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