PRO-E0256
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More information| Catalogue No. | PRO-E0256 |
|---|---|
| EC | 4.2.1.84 |
| Synonyms | Nitrilase; 3-cyanopyridine hydratase; NHase; LNHase; H-NHase; acrylonitrile hydratase; aliphatic nitrile hydratase; nitrile hydro-lyase; aliphatic-amide hydro-lyase (nitrile-forming) |
| Nomenclature | Fe-type |
| Specific Activity | > 4 U/mg (freeze-dried CFE) |
| Accession No. | Q7AZY7 (?-subunit); Q7AZY6 (?-subunit) |
| Molecular Weight | 23487.3 Da (?-subunit) | 25159.4 Da (?-subunit) |
| Biological Function | Hydrates nitriles | converting them into their corresponding acid amides (note: does not act on these amides) |
| Comments | Fe-type nitrile hydratase. Active on aryl and alkyl nitriles. Active in water/DMSO mixtures. Monohydration of bisnitriles. Selective nitrile hydration in the presence of ester functionality. Chemo- and stereoselective. This enzyme is heterodimeric | comprising one ?- and one ?-subunit. |
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