PRO-E0254
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More information| Catalogue No. | PRO-E0254 |
|---|---|
| EC | 4.2.2.1 |
| Synonyms | Hyaluronidase [but cf. EC 3.2.1.35 (hyalurononglucosaminidase) and EC 3.2.1.36 (hyaluronoglucuronidase)]; glucuronoglycosaminoglycan lyase; spreading factor; mucinase |
| Nomenclature | CAZy [PL8 | polysaccharide lyase family 8] | SCO5534 | SC1C2.15 |
| Specific Activity | 8.1 U/mg |
| Accession No. | O86516 | NP_629668.1 | SCOE100226:SCO5534-MON |
| Molecular Weight | 82914.2 Da |
| Biological Function | Cleaves hyaluronate chains at a ?-D-GalNAc-(1 4)-?-D-GlcA bond | ultimately breaking the polysaccharide down to 3-(4-deoxy-?-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine |
| Comments | This enzyme is active against hyaluronan | chondroitin-4 sulphate and chondroitin-6 sulphate and comprises two domains ? an N-terminal catalytic domain | and a C-terminal domain of as yet unclear function |
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