EREDs – Ene-reductases
Become a toolkit userOur ERED screening kit comprises 120 novel wild-type enzymes covering both FMN- and non-flavin EREDs. This panel is also under heavy development, with a target of 384 EREDs by Q4 2024!
History of the Prozomix ERED Kit
Publications involving Prozomix EREDs
Enantioselective Enzymatic Reduction of Acrylic Acids – Org Lett. – 2020
An asymmetric sp3–sp3 cross-electrophile coupling using ‘ene’-reductases – Nature – 2023
Regioselective Radical Alkylation of Arenes Using Evolved Photoenzymes – JACS – 2023
Regiodivergent Radical Termination for Intermolecular Biocatalytic C–C Bond Formation – JACS – 2024
Contact1. First set of EREDs cloned, expressed and offered commercially – 41 enzymes (2010)
2. Metagenomic expansion of ERED kit – 60 enzymes (2018)
3. Further development of metagenomic EREDs from both FMN- and non-FMN families – 96+ enzymes (2019-22)
Looking for a specific enzyme?
If you can not find a specific enzyme of interest, from our panels or from published work (or even your own work!). Please reach out to our team – info@prozomix.com.
In most cases, if we are missing what you are looking for, we will develop the missing product at our cost under our standard toolkit terms, in as little as two weeks!